患有ADHD和同时出现的运动困难的青少年在皮质脊髓管内表现出不同的成熟模式,与没有的青少年不同:基于固定物的纵向研究
Christian Hyde1, Ian Fuelscher1, Daryl Efron2,3,4
1Centre for Social and Early Emotional Development, School of Psychology, Deakin University, Geelong, Victoria, Australia.
Human brain mapping
|August 23, 2023
概括
注意缺陷多动症 (ADHD) 与运动困难有关. 这项研究发现,ADHD儿童的皮质-脊柱管 (CST) 中的白质差异,这可能解释了运动技能障碍.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿科 儿科 儿科
背景情况:
- 注意缺陷多动症 (ADHD) 经常与运动困难同时发生.
- 对于ADHD中运动能力受损的潜在生物机制尚不清楚.
- 了解这些机制对于解决ADHD患者的运动障碍至关重要.
研究的目的:
- 通过检查白质发育来研究ADHD运动问题的神经生物学基础.
- 在有或没有ADHD,有或没有运动困难的青少年中描述皮层-脊柱管 (CST) 的发展.
- 为了确定这些群体之间的CST白质组织和成熟的差异.
主要方法:
- 纵向高角度分辨率扩散MRI (dMRI) 数据从60名儿童 (年龄在9-14岁) 在三个时间点中收集.
- 参与者包括患有ADHD的儿童 (有和没有运动问题) 和典型的发展对照 (有和没有运动问题).
- 基于dMRI数据的固定分析被用于评估CST中的白质组织 (纤维密度和横截面).
主要成果:
- 在大约10岁时,ADHD儿童在CST中显示较低的纤维密度,与对照组相比,无论运动状态如何.
- 这些在CST的微观结构异常持续到青春期的个人与ADHD和同时发生的运动问题.
- 对于患有ADHD但没有运动问题的人来说,CST微观结构异常在青春期得到解决.
结论:
- 皮层-脊柱管的不同成熟路径可能会导致ADHD患者的运动问题.
- 这些发现表明,CST中白质的发展在ADHD和运动困难之间的关系中起着作用.
- 这些见解可以为与ADHD相关的运动障碍提供有针对性的干预措施.
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