与他类药物相关的肌肉并发症伪装成软组织肉瘤
Elizabeth Christophel1, Cassidy Ladas1, Francis Patterson1
1Hackensack Meridian Health Department of Orthopedic Oncology, 20 Prospect Avenue, Suite 901, Hackensack, NJ 07601, United States of America.
Trauma case reports
|August 23, 2023
概括
长期使用他类药物可能会导致无创性肌肉破裂,模仿血瘤等癌症症状. 该指南有助于医生区分他类药物诱导的伤害与恶性瘤,从而避免不必要的瘤转诊.
科学领域:
- 整形外科 整形外科 整形外科
- 肌肉骨医学 肌肉骨医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 长期使用他类药物治疗与肌肉骨损伤有关.
- 创伤后肌肉破裂和四肢血液瘤可以模仿瘤紧急情况.
- 区分他类药物诱导的伤害与恶性瘤对于适当的患者管理至关重要.
研究的目的:
- 为了区分他类药物诱导的肌肉破裂与恶性瘤,在患者呈现无创伤的伤害.
- 为管理长期使用他类药物的医生提供指导,这些医生有肌肉骨症状和出血性MRI发现.
- 为了减少不必要的转诊到骨科瘤学.
主要方法:
- 对两名因他类药物诱导的肌肉损伤而疑似患有恶性瘤的患者的案例研究综述.
- 对临床和成像发现的比较分析,区分他类药物诱导的肌肉破裂与恶性瘤.
- 讨论诊断细节和陷的讨论.
主要成果:
- 两个案例说明了因使用他类药物而导致的无创性肌肉破裂如何表现为恶性瘤的症状和MRI发现.
- 关键的区别特征包括在MRI上没有结节或质状增强.
- 肌肉骨症状可能是非特异性的,并随着保守的管理而改善.
结论:
- 医生应考虑在长期使用者中使用他类药物诱导的肌肉损伤,呈现无创性肌肉骨症状和出血性MRI发现.
- 仔细评估可以帮助避免误诊和不必要的瘤检查.
- 虽然在不确定的情况下,骨科瘤学转诊很重要,但可能并不总是需要.
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