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Updated: Jul 18, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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成人的时钟调节器将昼夜节律与胰腺β细胞成熟联系起来

Ana P Montalvo Landivar1,2, Zihan Gao3,4,5,2, Mai Liu3,4,5,2

  • 1Department of Neurosurgery, Brigham and Women's Hospital; Boston, MA 02115, USA.

bioRxiv : the preprint server for biology
|August 23, 2023
PubMed
概括

时钟因子DEC1对于成年小岛贝塔细胞成熟和葡萄糖控制至关重要. 它的缺失会导致终身的葡萄糖不耐受性,因为它将胰岛素分泌与新陈代谢脱.

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