相关实验视频

Updated: Jul 18, 2025

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
08:56

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues

Published on: December 5, 2016

11.0K

具有m6A核酸的METTL3-METTL14的结构揭示了对m6A转化和传感的洞察力

Shan Qi1,2, Abhay Kumar1,2, Shuang Chen3

  • 1Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA.

Research square
|August 23, 2023
PubMed
概括

酶复合体METTL3-METTL14在RNA上产生m6A标记. 一个新的结构揭示了这种甲基化是如何感知,提供了关于影响RNA调节的癌症相关突变的见解.

关键词:
酶的机制 酶的机制基因组RNA的修改 基因组RNA的改变在X射线晶体学.m6A 一个很好的.

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