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Updated: Jul 18, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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S-PLM:通过序列和结构之间的对比学习实现结构意识的蛋白质语言模型

Duolin Wang, Mahdi Pourmirzaei, Usman L Abbas

    bioRxiv : the preprint server for biology
    |August 23, 2023
    PubMed
    概括

    我们开发了S-PLM,这是一种新的3D结构感知蛋白质语言模型 (PLM),它集成了蛋白质序列和结构数据. 这种方法提高了蛋白质功能预测和设计能力,超出了传统的仅序列模型.

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