全血细胞计数参数在预测复杂急性尾炎的价值;一个预后准确性研究
Natchanok Mekrugsakit1, Thawatchai Tullavardhana1
1Department of Surgery, Faculty of Medicine, Srinakharinwirot University, Ongkharak Nakhon-nayok, Thailand.
Archives of academic emergency medicine
|August 23, 2023
概括
像白细胞 (WBC) 和中性细胞与淋巴细胞比率 (NLR) 这样的简单血清标志物在预测复杂尾炎时显示出有限的准确性. 需要进一步的研究来改善尾炎的诊断工具.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 临床病理学 临床病理学
- 手术紧急情况 手术紧急情况
背景情况:
- 准确诊断尾炎对于预防并发症至关重要.
- 临床变量的准确性较低可能导致诊断延迟,并增加复杂尾炎的发生率.
研究的目的:
- 评估复杂尾炎全血细胞计 (CBC) 生物标志物的预测值.
- 为了评估白细胞计数 (WBC),中性粒细胞百分比,中性粒细胞与淋巴细胞比率 (NLR),血小板与淋巴细胞比率 (PLR) 和平均血小板体积 (MPV) 在预测复杂尾炎的准确性.
主要方法:
- 单中心回顾性横截面研究.
- 包括接受尾切除的急性尾炎患者到急诊室的患者.
- 分析CBC变量,包括WBC,中性粒细胞百分比,NLR,PLR和MPV.
主要成果:
- 与其他测试的生物标志物相比,中性粒细胞计数 (AUC=0.61) 和NLR (AUC=0.65) 在预测复杂尾炎方面表现出更高的准确性.
- 白血细胞计数,血小板计数,PLR和MPV在预测复杂尾炎的准确性较低 (AUC<0.60).
- 复杂的尾炎病例表现出更长的症状发作,更高的白血球,更高的中性粒细胞数量和更高的NLR.
结论:
- 该研究表明,通常使用的CBC生物标志物,包括WBC,中性粒细胞百分比,NLR,PLR和MPV,在预测急诊室设置中的复杂尾炎时的准确性有限.
- 这些发现表明需要改进诊断标志物或用于识别复杂尾炎的策略.
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