从年龄和性别角度分析肺结核病例的流行病学和协会规则分析:中国的一项大型回顾性多中心观察性研究
Wanli Kang1, Jiajia Yu1, Chen Liang1
1Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China.
International journal of clinical practice
|August 23, 2023
概括
这项研究分析了中国的结核病例,发现近30%的人患有并发性肺结核 (PTB) 和肺外结核 (EPTB) 形式. 根据患者人口统计数据,PTB和特定EPTB类型之间的关联有所不同,这凸显了全面查的必要性.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 结核病 (TB) 是一个重要的全球健康问题,具有不同的临床表现.
- 同时肺结核 (PTB) 和肺外结核 (EPTB) 是常见的,但尚未得到充分了解.
- 这项研究调查了中国同期PTB-EPTB的流行病学.
研究的目的:
- 分析PTB-EPTB病例并发的流行病学特征.
- 通过使用关联规则来识别PTB和各种EPTB类型之间的关联.
- 了解这些关联如何因人口因素而有所不同.
主要方法:
- 一个大规模的,多中心的回顾性观察性研究在中国 (2011-2017).
- 包括所有已确认结核病诊断的住院患者.
- 在并发的PTB-EPTB案例上应用阿普里奥里算法进行协会规则分析.
主要成果:
- 在438,979名结核病住院患者中,有29.48%的人同时患有PTB-EPTB.
- 结核性肺炎是最常见的并发性EPTB.
- PTB和EPTB类型 (例如支气管,喉/喉) 之间的关联因性别和年龄而异.
结论:
- 同时的PTB-EPTB是普遍存在的,具体的关联受性别和年龄的影响.
- 识别这些关联可以提高对结核病共感染的理解.
- 临床医生应对并发性PTB-EPTB进行查,以提高患者治疗结果.
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