Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.7K
The Nucleolus02:55

The Nucleolus

8.9K
The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...
8.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Endogenous stimuli-responsive intelligent drug delivery systems: recent advances in cleavable linker design.

Chemical communications (Cambridge, England)·2026
Same author

Nucleus-targeted protein delivery <i>via</i> lysine dendron conjugation.

Chemical communications (Cambridge, England)·2025
Same author

Self-assembly of enzymes and prodrugs with clickable amino acids for nucleus-targeted cancer therapy.

Chemical communications (Cambridge, England)·2024
Same author

Nucleus-selective self-augmenting cascade nanoassemblies for targeted synergistic photo-chemo therapy of tumors.

Chemical communications (Cambridge, England)·2023
Same author

Nucleus-selective codelivery of proteins and drugs for synergistic antitumor therapy.

Chemical science·2022
Same author

The First FRET-Based RNA Aptamer NanoKit for Sensitively and Specifically Detecting c-di-GMP.

Nano letters·2022

相关实验视频

Updated: Jul 18, 2025

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.6K

核心向瘤治疗的研究进展.

Shaofeng Chen1, Rumeng Cao1, Ling Xiang1

  • 1Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, P. R. China. zhangjm@cqu.edu.cn.

Biomaterials science
|August 23, 2023
PubMed
概括

核向药物递送系统 (NDDS) 在精准医学方面表现有前途. 克服生物障碍,将治疗药物输送到核中,是有效的核向治疗的关键.

科学领域:

  • 细胞生物学 细胞生物学
  • 药理学 药理学是指药理学的学科.
  • 生物技术是生物技术.

背景情况:

  • 核是一个关键的器官,调节细胞功能,如生殖和新陈代谢.
  • 针对药物输送的核提供了重要的治疗潜力,在精准医学.
  • 生物障碍阻碍了治疗药物的有效运输到细胞核.

研究的目的:

  • 审查核向药物递送系统 (NDDS) 的最新进展.
  • 为了阐明药物运输在核包裹中的机制.
  • 讨论当前面临的挑战和有效的NDDS的未来解决方案.

主要方法:

  • 核心和核外结构的描述.
  • 针对细胞核的药物输送策略的分析.
  • 关于NDDS的最新文献的审查.

主要成果:

  • 了解核结构有助于设计有效的药物输送机制.
  • 为了穿越核包裹,存在各种策略,具有多样化的应用.
  • 在实现有效的细胞核向和临床转化方面,仍然存在重大挑战.

结论:

更多相关视频

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

6.6K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.4K

相关实验视频

Last Updated: Jul 18, 2025

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.6K
Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

6.6K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.4K
  • 核向药物输送对精准医学有很大的前景.
  • 克服生物障碍对于开发有效的NDDS至关重要.
  • 需要进一步的研究来提高NDDS的效率,并促进临床应用.