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Updated: Jul 18, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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Published on: June 8, 2022

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不正常的淋巴神经1-信号加剧淋巴功能障碍和组织炎症

Dongeon Kim1,2, Wen Tian1,2, Timothy Ting-Hsuan Wu2,3

  • 1VA Palo Alto Health Care System, Palo Alto, CA (D.K., W.T., M.X., R.V., J.L.C., S.G., S.L., Y.Z., T.G., E.C.S., E.B., J.P., X.J., M.R.N.).

Circulation
|August 23, 2023
PubMed
概括

在淋巴内皮细胞 (LEC) 中减少的基-1-酸盐 (S1P) 信号通过增加细胞粘附和T细胞激活加剧淋巴. P-选择因抑制剂对治疗这种疾病具有前景.

关键词:
P-选择素T 淋巴细胞淋巴内皮细胞淋巴斯芬戈辛-1-酸盐受体 1

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