在自闭症谱系障碍中对脊椎病的分析
Keith Orland1, Kaela Harvey2, Lydia N Klinkerman1
1Scottish Rite for Children.
Journal of pediatric orthopedics
|August 23, 2023
概括
患有自闭症谱系障碍 (ASD) 和脊柱病的儿童在脊柱融合后显示出更好的曲线校正,而非异常脊柱病患者相比. 两年后的放射结果相似,ASD组没有增加并发症.
科学领域:
- 整形外科手术 整形外科手术
- 儿科脊柱形症 儿童脊柱形症
- 自闭症谱系障碍研究研究
背景情况:
- 自闭症谱系障碍 (ASD) 诊断包括患有自闭症/阿斯伯格症的儿童.
- 关于与异常学性脊椎病 (IS) 相比,ASD儿童脊椎病的放射和临床结局存在不确定性.
研究的目的:
- 为了比较脊柱融合的放射和临床结果,ASD和脊柱病的儿科患者与IS患者相比,ASD和脊柱病的儿童患者.
- 为了评估经过脊髓融合的ASD患者的手术结果和并发症率.
主要方法:
- 在一个单一的中心,回顾前性脊椎病注册 (1990-2021年) 的回顾性审查.
- 包括接受后脊髓融合±前脊髓融合的ASD患者.
- 根据年龄和性别,与异常学脊椎病 (IS) 患者进行2:1匹配,以比较人口统计学,放射学,手术内和SRS-22/30变量.
主要成果:
- 30名ASD患者 (平均年龄14.6岁) 与匹配的IS患者进行了比较.
- 自闭症患者在2年的随访中实现了更大的曲线校正 (66%对57%,P=0.01) 与较小的平均曲线大小 (20°对27°,P<0.01).
- 在ASD和IS队列之间的2年随访中,没有观察到在sagittal参数或并发症率上的显著差异.
结论:
- 患有ASD和脊椎病的儿科患者在2年的随访中表现出与IS患者相似的放射性结果.
- 与IS患者相比,ASD患者在脊髓融合后实现了优越的曲线校正.
- 在ASD患者中,手术前腰部主症的降低在2年随访后正常化.
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