在没有临床视网膜病变的糖尿病患者和非糖尿病患者之间比较中央黄斑厚度
Upasana Pokhrel1, Eli Pradhan, Rabindra Singh Thakuri
1B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
概括
通过监测中央黄斑厚度 (CMT),可以改善糖尿病视网膜病变 (DR) 的检测. 这项研究发现,CMT最初下降,然后随着糖尿病持续时间的增加而增加,这表明它.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 糖尿病视网膜病变 (DR) 是工作年龄成人失明的主要原因.
- 早期发现DR对于预防视力丧失至关重要.
- 糖尿病持续时间是DR发展和进展的重要预测因素.
研究的目的:
- 在没有糖尿病视网膜病变临床症状的患者中,研究糖尿病持续时间和中央黄斑厚度 (CMT) 之间的关系.
- 评估光谱域光学一致性断层扫描 (SD-OCT) 在评估糖尿病早期黄斑变化的有用性.
主要方法:
- 一项涉及182名患者 (364只眼睛) 的三级转诊中心的横截面研究.
- 患者被分为没有视网膜病变的糖尿病组和非糖尿病对照组.
- 使用光谱域光学一致性断层扫描 (SD-OCT) 测量了中央黄斑厚度 (CMT),并将其与各组进行了比较.
主要成果:
- 没有视网膜病变的糖尿病患者的CMT平均值为236.29±40.31μm,而非糖尿病对照组的CMT平均值为244.25±30.51μm.
- 在糖尿病患者中,CMT显示了糖尿病持续时间小于1年的糖尿病患者的初始降低 (217.19±42.22μm).
- 随着糖尿病持续时间的延长,CMT逐渐增加,在6-15岁之间达到顶峰,然后略有下降.
结论:
- 中部黄斑厚度 (CMT) 最初呈现下降,随后随着糖尿病持续时间的推进而增加.
- 使用SD-OCT测量黄斑厚度可以作为一种有价值的工具,用于在临床症状出现之前监测DR进展.
- 这种成像模式有助于早期发现和治疗糖尿病视网膜病变.
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