金属混合物与婴儿负面情感之间的关联:由产前皮质醇和婴儿性别修饰效果
Francheska M Merced-Nieves1, Samuel Eitenbichler2, Brandon Goldson2
1Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Child development
|August 23, 2023
概括
产前暴露于金属和皮质醇会影响婴儿的社会情感发展,特别是在女孩身上. 较高的母体皮质醇和金属混合物暴露与女婴的恐惧和悲伤增加有关.
科学领域:
- 环境健康 环境健康
- 神经发育科学 神经发育科学
- 围产期心理学 围产期心理学
背景情况:
- 在子宫内暴露极大地影响神经发育.
- 胎儿的性别是环境影响对社会情感结果的已知调节者.
- 人类对关节金属和压力因素暴露的数据有限.
研究的目的:
- 调查产前金属混合物暴露和母体皮质醇对婴儿负面情感的联合影响.
- 检查这些暴露与社会情感结果之间的关系的性别特异性差异.
- 为了进一步了解复杂的子宫内环境相互作用.
主要方法:
- 对226对母婴对进行分析.
- 评估产前金属混合物和皮质醇水平.
- 使用婴儿行为调查问卷对婴儿负面情感的评估 - - 经过6个月的修订.
主要成果:
- 较高的母体皮质醇水平与女孩的婴儿恐惧和悲伤得分增加有关.
- 这种关联在与更大的产前接触金属混合物时更为明显.
- 在男婴中没有观察到任何显著的关联.
结论:
- 产前金属混合物和皮质醇暴露共同影响婴儿的社会情绪功能,有明显的性别差异.
- 女婴可能更容易受到这些暴露的综合影响.
- 对更高层次相互作用的进一步研究是有必要的,以充分理解这些发育影响.
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