退伍军人人口中的胃癌风险因素
Kush Fansiwala1, Yingzhi Qian2, Peter S Liang2,3,4
1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Military medicine
|August 23, 2023
概括
黑人和亚洲人种族,以及当前或从未饮酒是胃癌的危险因素. 根除Helicobacter pylori和恶性贫血可能会降低风险. 需要对美国人口进行进一步的研究.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 美国胃癌 (GC) 的危险因素尚不清楚,特别是在非移民人群中.
- 在退伍军人事务医疗中心进行了一项匹配的病例控制研究,以调查GC风险因素.
研究的目的:
- 确定与胃癌发展相关的人口,医疗和生活方式风险因素.
- 探索潜在的保护因素,防止胃癌.
主要方法:
- 一个匹配的病例控制研究设计,胃癌患者与对照者的比例为1:4.
- 提取的数据包括人口统计,医学,内镜和组织学信息.
- 条件后勤回归分析用于估计赔率比率和95%置信区间.
主要成果:
- 胃癌经常在初始内镜检查 (71.4%) 后被诊断为晚期 (第四阶段:40.8%).
- 确定的风险因素包括黑人和亚洲人种族,以及目前或从未饮酒的酒精消费 (与以前的饮酒者相比).
- 杆菌根除和恶性贫血与胃癌风险降低有关.
结论:
- 胃癌晚期诊断需要在美国改善风险分层,查和监测协议.
- 退伍军人胃癌发病率的种族差异需要进一步调查潜在原因.
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