处理爱抚般的触摸的大脑机制在皮肤摘取障碍中的皮肤摘取障碍
Anne Schienle1, Carina Schlintl2, Albert Wabnegger2
1Clinical Psychology, University of Graz, BioTechMed, Universitätsplatz 2/III, 8010, Graz, Austria. anne.schienle@uni-graz.at.
European archives of psychiatry and clinical neuroscience
|August 23, 2023
概括
患有皮肤摘取障碍 (SPD) 的人对温柔的触摸表现出改变的大脑反应,表现出增加的头顶活动和减少的前部停活. 这表明SPD的感官处理和注意力控制受损.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 皮肤病学 皮肤病学
背景情况:
- 皮肤摘取障碍 (SPD) 涉及重复的皮肤摘取,通常导致组织损伤.
- 触摸的感官体验,特别是像爱抚一样的刺激,在SPD中被了解得很少.
- 触觉感应器 (C-tactile afferents) 参与处理愉快的,温柔的触觉.
研究的目的:
- 用功能磁共振成像 (fMRI) 来研究SPD女性对爱抚般触摸的神经反应.
- 为了在触觉刺激期间比较SPD和健康对照个体之间的大脑激活模式.
- 探索触觉处理,感官评级和SPD中挑皮的冲动之间的关系.
主要方法:
- 70名SPD女性和62名健康女性接受了fMRI扫描.
- 参与者在前臂上接受了CT-最佳 (3厘米/秒) 和非最佳 (30厘米/秒) 的刷毛.
- 对快乐,兴奋和挑选冲动的主观评分是在刺激后收集的.
主要成果:
- 与对照组相比,SPD患者在CT-最佳触摸期间表皮区域 (上边缘/角) 的活化更大.
- 对照组在中/下额叶皮层表现出失活,而SPD组没有这种情况.
- 被触摸被评为不那么愉快,更令人兴奋,并增加了SPD患者皮的冲动.
结论:
- SPD与轻柔的,像爱抚一样的触摸的功能障碍处理有关.
- 额头和额头注意力控制区域的激活变化可能是SPD感官处理缺陷的基础.
- 这些发现有助于了解皮肤挑选障碍中触觉功能障碍的神经生物学基础.
相关概念视频
Somatosensation
36.7K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.7K
Sensory Functions of the Skin
5.1K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
5.1K
Sensory Perception: Organization of the Somatosensory System
3.1K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
3.1K
Major Somatic Sensory Pathways
1.0K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.0K
Tactile and Chemical Senses
321
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
321
Overview of Somatic Sensory Pathways
4.6K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.6K


