书面暴露治疗与治疗创伤后应激障碍的长期暴露治疗:一项随机临床试验
Denise M Sloan1,2,3, Brian P Marx1,2,3, Ron Acierno4,5
1Veterans Affairs (VA) Boston Healthcare System, Boston, Massachusetts.
JAMA psychiatry
|August 23, 2023
概括
书面暴露疗法 (WET) 与长期暴露疗法 (PE) 在治疗退伍军人的创伤后应激障碍 (PTSD) 中同样有效. 此外,WET也显示出明显较低的学率,使其成为更容易获得的治疗选择.
科学领域:
- 精神病学和行为科学
- 临床心理学 临床心理学
- 创伤研究 创伤研究
背景情况:
- 基于证据的创伤后应激障碍 (PTSD) 治疗方法通常是漫长的,导致完成率较低.
- 书面暴露治疗 (WET) 提供了一个简短,有效的替代方案,但尚未与长期暴露治疗 (PE) 进行直接比较.
研究的目的:
- 确定书面暴露疗法 (WET) 是否在减轻退伍军人中PTSD症状方面与长期暴露疗法 (PE) 相比无差.
- 为了比较WET和PE之间的治疗完成率.
主要方法:
- 一个随机的非劣等性试验,涉及178名被诊断患有PTSD的退伍军人在三个退伍军人事务医疗中心.
- 参与者被分配到WET (5-7次) 或PE (8-15次).
- 通过DSM-5 (CAPS-5) 临床医生管理的PTSD尺度 (CAPS-5) 测量的主要结局是从基线到20周的变化.
主要成果:
- 在减少PTSD症状严重程度方面,WET被发现与PE无差.
- 在10周的评估中,减轻症状的最大差异有利于WET (平均差异2.42分).
- 与PE (35.6%) 相比,较少的参与者放弃了WET (12.5%).
结论:
- 书面暴露疗法 (WET) 是患有PTSD的退伍军人长期暴露疗法 (PE) 的可行和有效替代方案.
- 由于WET的简短性和较低的消耗率表明,它可以克服完成PTSD治疗的常见障碍.
- 研究结果支持WET作为潜在的PTSD更容易获得的治疗方法.
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