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使用不同治疗方法的1型糖尿病患者的葡萄糖监测指标:现实世界的观察性研究
Kirsten Nørgaard1,2, Ajenthen G Ranjan1, Christian Laugesen1
1Copenhagen University Hospital, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Diabetes care
|August 23, 2023
概括
自动化胰岛素输送系统 (AID) 与其他用于1型糖尿病管理的胰岛素方法相比,显示出更好的血糖控制. 艾滋病提供了更好的范围和达到血糖目标的时间,使其成为首选选择.
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病 技术 技术
- 代谢医学是一种代谢医学.
背景情况:
- 持续血糖监测 (CGM) 提供了关于血糖控制的宝贵现实数据.
- 对于1型糖尿病,存在不同的胰岛素治疗方式,每一种对葡萄糖管理的影响各不相同.
研究的目的:
- 研究CGM衍生的血糖指标与各种胰岛素治疗策略之间的关联.
- 为了比较多次每日注射 (MDI),传感器增强 (SAP) 和自动胰岛素输送 (AID) 在1型糖尿病管理中的有效性.
主要方法:
- 一项横截面研究分析了使用CGM的3,184名1型糖尿病患者的真实世界数据.
- 参与者被分为MDI,胰岛素与非集成的CGM (SUP),SAP和AID组.
- 主要结局是范围内的时间 (TIR);次要结局包括其他葡萄糖指标和HbA1c.
主要成果:
- 自动胰岛素输送 (AID) 用户实现了最高的中位时间在范围 (72.1%).
- 与MDI用户相比,SAP和AID用户的比例明显高于MDI用户,他们达到所有血糖目标.
- 实现目标的几率比率为SAP的2.4,AID的9.4,与没有警报的MDI相比.
结论:
- 自动注射胰岛素 (AID) 与其他胰岛素治疗方式相比,在与CGM一起使用时显示出更好的血糖控制.
- 应考虑AID为1型糖尿病患者的首选胰岛素治疗选择.
- 虽然存在潜在的偏见,但数据强烈支持AID在改善糖尿病管理方面的有效性.
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