登革热患者粘膜皮肤表现的描述性和比较分析:一项前性研究
C Fera1, O Maillard2, E Joly1
1CHU Réunion, Service des Maladies Infectieuses - Dermatologie, Saint Pierre, La Réunion, France.
概括
登革热经常引起广泛的皮肤症状,超过80%的患者出现粘膜皮肤症状. 虽然这些症状很常见,但只有湿疹性紫外线表明严重登革热的风险.
科学领域:
- 登革热病毒研究研究
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 登革热是一种影响全球健康的重要树冠病毒性疾病.
- 鲁尼昂岛自2018年以来经历了登革热病例的复苏.
- 粘膜皮肤表现,通常称为"皮疹",在不同研究中发生率不同.
研究的目的:
- 在登革热患者中确定各种粘膜皮肤症状的患病率.
- 为了描述表现出这些症状的患者.
- 为了识别与严重登革热相关的临床症状.
主要方法:
- 2019年在拉里昂岛大学医院进行的一项前性研究.
- 纳入标准:阳性登革热PCR的患者.
- 所有参与者都被皮肤科医生评估;进行了描述性分析.
主要成果:
- 分析了163例登革热病例,其中80.4%的病例表现出粘膜皮肤症状.
- 常见的症状包括 (33.7%),红血性皮疹 (29.4%) 和口腔卷入 (31.3%).
- 粘膜皮肤症状与严重的登革热没有相关性,但湿疹性紫外线有 (p=0.037).
结论:
- 登革热感染与皮肤症状的高流行率和多样性有关.
- 在不严重的情况下,粘膜皮肤干扰通常伴随着显著的类似流感的综合征.
- 识别湿疹性紫外线或粘膜脱水对于预测严重登革热进展至关重要.
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