在降低乳房整形中优化组织氧化:氧气持续扩散的作用:可行性试点随机对照试验
Alejandro Zulbaran-Rojas1, Rasha O Bara1, Myeounggon Lee1
1Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
The Journal of surgical research
|August 23, 2023
概括
持续扩散氧 (CDO) 是接受双边缩小乳房整形术 (BRM) 的患者可行的安全疗法. 虽然CDO增强了乳腺组织的氧化,但它对伤口脱光的影响需要进一步研究.
科学领域:
- 整形外科 整形外科 整形外科
- 伤口愈合 治愈 伤口愈合
- 生物医学工程 生物医学工程
背景情况:
- 双边减小乳房整形术 (BRM) 是为了缓解巨乳的症状而进行的.
- 在12% - 39%的BRM手术中,T结线的伤口损伤发生,通常是由于输液减少.
- 持续扩散氧 (CDO) 可以改善组织氧化和预防伤口并发症.
研究的目的:
- 探索在接受BRM的妇女的T结处自我应用的CDO治疗的可行性,安全性和可接受性.
- 评估CDO对T结组织氧化和伤口脱光的影响.
主要方法:
- 进行了一项为期4周的可行性试点随机对照试验,其中16名参与者接受了BRM.
- 一个乳房接受了标准护理 (SOC),而另一个乳房接受了SOC + CDO (或覆盖或直接应用).
- 可行性结果包括协议交付,结果测量,不良事件和设备可接受性. 探索性结果包括组织氧化 (SatO2,脱氧血红蛋白) 和伤口脱色.
主要成果:
- 协议交付率为93.7%,结果测量率为100%,并且没有发生与设备相关的不良事件.
- 设备的接受度很高,在使用态度方面达成了85.4%的共识,在易用性方面达到了78.2%,在实用性方面达到了77.7%.
- 与其他组相比,覆盖的CDO (sCDO) 显著增加了Sato2和降低了脱氧血红蛋白 (P < 0.001),但伤口脱光率没有显著差异 (P = 0.66).
结论:
- 对于接受BRM的患者来说,对T结的自我应用的CDO是可行的,安全的和可接受的.
- 在合适的伤口环境中,CDO有可能增强乳腺组织的氧化.
- 需要进一步的研究来确定CDO是否减少伤口脱光,这项研究支持更大的随机试验.
更多相关视频
13:21Affordable Oxygen Microscopy-Assisted Biofabrication of Multicellular Spheroids
Published on: April 6, 2022
3.4K
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
1.6K
相关概念视频
01:17Assessment of Diffusion and Perfusion
1.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.0K
01:16Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
688
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
688
01:26Oxygen Delivering System I: Nasal Cannula and Face Mask
384
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
384
01:30Administering Oxygen by Mask
440
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
440
01:20Gas Exchange and Transport
70.3K
Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
70.3K
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
263
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
263