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用于检测皮质醇的电化学传感器:原理,设计,制造和表征

Gopi Karuppaiah¹, Min-Ho Lee², Shekhar Bhansali³

¹Electrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute (CECRI), Karaikudi, 630 003, Tamil Nadu, India; School of Integrative Engineering, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.

Biosensors & bioelectronics

|August 23, 2023

概括

电化学传感器为检测皮质醇提供了一种有前途的方法,皮质醇是一种关键的压力生物标志物. 这项技术旨在为更容易获得的 Point-of-care 压力管理和个性化医疗保健解决方案.

科学领域:

生物医学工程生物医学工程
分析化学分析化学
神经内分泌学神经内分泌学

背景情况:

心理压力显著影响健康,由像皮质醇这样的压力激素介导.
皮质醇是一种关键的生物标志物,调节身体的战斗或逃跑反应,对压力管理至关重要.
准确的皮质醇检测对于个性化医疗保健和理解与压力相关的健康差异至关重要.

研究的目的:

审查用于皮质醇检测的电化学传感器的进展.
分析这些传感器的设计,原理和方法.
确定电化学皮质醇传感的挑战和未来方向.

主要方法:

对用于检测皮质醇的电化学传感技术的审查.
分析传感器设计,电分析方法和性能指标.
讨论包括生物污染,敏感性和材料开发在内的挑战.

主要成果:

电化学传感是一种可靠的方法,用于在医院检测皮质醇.
在传感器设计和分析性能方面取得了重大进展.
关键的挑战仍然在于灵敏度,稳定性和现实世界的应用程序翻译.

结论:

在压力管理中,电化学传感器对于可访问的皮质醇监测至关重要.
需要进一步开发敏感的电极和材料.
克服挑战对于将研究转化为临床应用至关重要.

关键词:

循环节律是循环节律的节奏.临床测量临床测量皮质醇是一种皮质醇.电化学传感器电化学传感器压力生物标志物是压力的生物标志物.可穿戴式传感器

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