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Updated: Jul 18, 2025

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CD73通过调节PI3K/AKT介导的肝细胞灭,减轻酒精性脂肪肝炎的肝损伤

Hong Zhu1, Mengda Zhang1, Ying Ye1

  • 1Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Institute for Liver Diseases of Anhui Medical University, Hefei 230032, China.

Biochemical pharmacology
|August 23, 2023
PubMed
概括

这项研究揭示了CD73 (Nt5e) 通过抑制肝细胞中的烧灭酶来保护免受酒精诱导的肝损伤. 向CD73为酒精性肝病 (ALD) 提供了一个新的治疗策略.

关键词:
在 AKT AKT 里面.细胞死亡 细胞死亡在炎症中,一些细胞会发炎.肝脏 肝脏 肝脏 肝脏在NLRP3中,NLRP3是NLRP3中的一个.

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