验证和确定低血糖意识问卷的诊断值 意识受损子表
Austin Matus1, Anneliese J Flatt2, Amy J Peleckis2
1Department of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania.
概括
低血糖意识问卷下降意识 (HypoA-Q IA) 分级有效地识别了1型糖尿病成年人低血糖意识的下降. 建议在HypoA-Q IA子尺度上设置12的诊断值,用于对低血糖症 (IAH) 的意识受损进行分类.
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病研究 糖尿病研究
- 临床心理学 临床心理学
背景情况:
- 低血糖症 (IAH) 的意识受损是1型糖尿病 (T1D) 的重要并发症.
- 准确的评估工具对于识别IAH至关重要,以防止严重的低血糖事件.
- 低血糖意识问卷认知障碍 (HypoA-Q IA) 亚尺度是此评估的一个潜在工具.
研究的目的:
- 评价HypoA-Q IA分级的歧视和收有效性.
- 建立一个诊断值来对患有T1D的成年人分类IAH.
- 为了验证HypoA-QIA亚尺度用于临床和研究用途.
主要方法:
- 21名患有T1D的成年人完成了HypoA-Q IA分级,克拉克得分,HYPO得分和持续血糖监测.
- 进行了超胰岛素性低血糖测试,以评估生理反应.
- 一项为期18个月的干预研究涉及IAH患者的重复评估.
主要成果:
- 根据HypoA-Q IA分级,有效地区分了IAH和没有IAH的个体 (P <.001).
- 通过与已确定的措施和生理反应的显著相关性,证明了趋同有效性.
- 12的HypoA-Q IA得分被确定为IAH分类的最佳门,敏感度为83%,特异性为80%.
结论:
- HypoA-Q IA分级是评估T1D中低血糖症意识受损的有效工具.
- 建议在HypoA-Q IA子尺度上为12的诊断值用于对IAH进行分类.
- 这种经过验证的工具可以在临床实践和研究环境中使用.
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