Cδδ

Angela M Ohm1, Trisiani Affandi1, Julie A Reisz2

  • 1Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

概括

蛋白激酶Cδ (PKCδ) 活性的丧失通过重编程细胞代谢来赋予放射电阻. 枯竭的PKCδ增强了酸通路和谷氨用于核酸合成的利用,有助于细胞抗击DNA损伤的生存.

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