布鲁内达鲁萨拉姆肺外结核病的流行病学:一个回顾性队列研究
Liling Chaw1, Lena Mat Salleh2,3, Rafizah Abdul Hamid3
1PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam liling.chaw@ubd.edu.bn.
BMJ open
|August 23, 2023
概括
肺外结核 (EPTB) 在文莱占结核病例的19%. 淋巴和肺部EPTB是最常见的,风险因素因年龄,性别和居住地而异. 公共意识对于早期诊断至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战.
- 肺外结核 (EPTB) 占结核病总负担的很大一部分.
- 了解EPTB流行病学对于有效的控制策略至关重要.
研究的目的:
- 确定布鲁内达鲁萨拉姆的肺外结核病 (EPTB) 发病率和相关因素.
- 分析EPTB病例按解剖部位的分布.
- 确定特定EPTB类型的人口和居住相关风险因素.
主要方法:
- 从2001年到2018年,对布鲁内达鲁萨拉姆所有活跃结核病例进行了回顾性队列研究.
- 计算EPTB和特定EPTB类型的年度比例.
- 多重逻辑回归分析以确定与EPTB相关的因素与肺结核 (PTB) 相比.
主要成果:
- 在3916例结核病例中,743例 (19.0%) 是EPTB,其中淋巴 (44.8%) 和肺部 (19.4%) 是最常见的.
- 年龄较小和女性性别与淋巴性EPTB的几率较高,但肺部EPTB的几率较低有关.
- 与外国居民相比,当地居民的骨,胃肠道和其他EPTB类型的几率更高.
结论:
- EPTB对结核病负担做出了重大贡献,需要具体的流行病学理解.
- 对EPTB的危险因素因解剖部位,年龄,性别和居住地而异.
- 促进早期症状识别和诊断的公众宣传活动对于管理EPTB至关重要.
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