虚弱性阿尔茨海默病:流行,查,评估,干预策略和挑战
Yi Deng1, Haiyin Wang2, Kaicheng Gu3
1Department of Geriatric Nursing, Hamamatsu University school of Medicine, Japan.
Bioscience trends
|August 23, 2023
概括
阿尔茨海默氏症 (AD) 和脆弱性经常并存,这加剧了这两种疾病的结果. 本综述涵盖了它们的流行,查和治疗,强调了更好的患者护理所面临的挑战和未来的研究需求.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 阿尔茨海默病 (AD) 是一种进展性神经退行性疾病,由于人口老龄化,其全球流行率正在增加.
- 脆弱性,由于生理储备下降而增加脆弱性的状态,也与年龄有关,并造成了重大负担.
- 阿尔茨海默病和虚弱的同时发生是常见的,超过30%的病例,这表明相互恶化关系.
研究的目的:
- 对阿尔茨海默病 (AD) 和脆弱性进行全面的文献审查.
- 为了检查患病率,查方法,评估工具和治疗策略,同时出现AD和脆弱性.
- 为了确定当前的挑战和未来的研究方向在管理这个双重条件.
主要方法:
- 对有关阿尔茨海默病和脆弱性的现有文献进行系统审查.
- 对患病率数据,查和评估工具 (例如,脆性表型,MMSE,MoCA) 和干预策略的分析.
- 探索诊断,管理和服务提供方面的挑战.
主要成果:
- 虚弱和AD在30%以上的个体中共存,具有显著的有害关联.
- 对于这两种情况,有许多查工具存在,但没有建立单一的黄金标准.
- 非药物干预措施 (营养,运动,社交互动) 是有前途的,而药物治疗需要进一步验证.
结论:
- 综合的查和管理方法对于同时出现AD和脆弱的个体至关重要.
- 多领域的非药物干预措施为认知和功能改善提供了潜力.
- 需要进一步的研究来解决诊断挑战,临床试验的局限性,并开发综合护理模型.
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