基于生物复合材料的牙骨再生策略
Seyed Ebrahim Alavi1, Seyed Zeinab Alavi2, Max Gholami1
1School of Medicine and Dentistry, Griffith University, Gold Coast, Australia.
Oral surgery, oral medicine, oral pathology and oral radiology
|August 23, 2023
概括
生物复合材料支架显示出牙骨再生的前景,为传统方法提供了更优质的替代方案. 像增材制造这样的先进技术提高了它们在修复复杂的口腔和面骨缺陷方面的有效性.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 口腔和牙面部外科手术
背景情况:
- 修复口腔和大面部区域的骨缺陷存在重大的解剖学挑战.
- 传统的骨再生方法,如自体移植和异体移植,具有局限性,包括捐赠部位的发病率,免疫排斥和有限的可用性.
- 生物复合材料为克服牙骨再生中的这些挑战提供了一个有希望的途径.
研究的目的:
- 审查和评估基于生物复合物的牙骨再生策略.
- 为了比较先进的生物复合材料支架与传统骨移植技术的有效性.
- 探索增材制造在提高口面部应用的生物复合材料支架性能方面的作用.
主要方法:
- 在主要的科学数据库 (Web of Science,PubMed,Scopus,Google Scholar) 中进行了全面的文献搜索.
- 分析了过去20年发表的研究论文,重点是牙骨再生的生物复合材料.
- 对单相,双相/多相支架和基于生物聚合物的纳米复合材料支架与传统方法进行了比较分析.
主要成果:
- 生物复合材料支架,包括单相,双相/多相和基于生物聚合物的纳米复合材料,在传统方法 (自移植,异构移植,异构移植,异构塑料) 上表现出优越性.
- 生物复合材料有效地解决了传统方法的局限性,例如有限的骨来源,疼痛,免疫反应和高成本.
- 纳米材料被纳入生物聚合物支架中,进一步增强了它们的再生潜力.
结论:
- 基于生物复合材料的策略对牙骨再生非常有效,超过了传统的治疗方法.
- 增材制造技术显著提高了生物复合材料支架的疗效,用于治疗复杂的牙骨缺陷.
- 这些先进的材料和制造方法代表了口腔和面整形手术的重大进步.
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