nebulized voriconazole 的表征和现实实验结果:一个单中心观察性研究
Maria Larrosa-Garcia1, Sònia Terradas Campanario1, Aurora Fernández Polo1
1Pharmacy Department, Vall d'Hebron University Hospital, Barcelona, Spain.
概括
雾化伏利可纳是一种安全且耐受性良好的治疗真菌性肺部疾病,没有观察到系统吸收. 需要进一步的研究来证实它在患者中的有效性.
科学领域:
- 肺部医学 肺部医学
- 菌类学 菌类学是指菌类学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 沃里可纳的肺部注射提供了潜在的好处,如改善肺部透率和减少全身副作用.
- 目前,有有限的临床证据和没有商业配方用于 nebulized voriconazole.
研究的目的:
- 描述一种用于雾化的复合伏里可纳溶液.
- 描述 nebulized voriconazole 在患有真菌性肺部疾病的患者的临床使用情况.
主要方法:
- 对接受 nebulized voriconazole 的患者进行了回顾性观察研究.
- 从静脉注射小瓶中制备的伏利康纳溶液.
- 剂量:40毫克 (成人) / 10毫克 (儿科) 每12-24小时.
主要成果:
- 复合溶液具有足够的pH值和度,可以进行雾化.
- 10名患者 (9名成年人,1名儿童) 接受治疗,平均治疗时间为139天.
- 没有报告任何不良反应,而沃里可纳在血中无法检测到.
结论:
- 雾化伏利可纳似乎被很好地容忍,并且不会被系统吸收.
- 需要进一步的研究,以确定雾化伏利可纳对真菌性肺部疾病的疗效.
关键词:
亚斯伯吉洛症 (Aspergillosis) 是一种疾病.复杂化是一种复杂化.菌性肺部疾病是一种真菌性肺部疾病.雾化器是一种雾化器.沃里康纳醇是一种沃里康纳 (Voriconazole) 是一种可以阿斯珀吉洛斯症 (aspergillosis) 是一种疾病.肺部真菌性肺部疾病 肺部真菌性肺部疾病司法官的表述 法官的表述一个雾化器.更多相关视频
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