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Updated: Jul 18, 2025

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一个双联多个核酸长度的多态性解释了在5p15.33前列腺癌风险位置的功能因果关系

Sandor Spisak1,2, Viktoria Tisza1,3,4, Pier Vitale Nuzzo1,2,5

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

Nature communications
|August 23, 2023
PubMed
概括

多核酸长度多态 (MNLP),而不仅仅是单核酸多态 (SNP),可以通过改变基因表达来增加前列腺癌的风险. 这些非SNP变异对于理解复杂疾病遗传学至关重要.

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