在诊断出胆囊癌后,非癌症死亡原因:基于人口的分析分析
Yang Xia1, Shuangshuang Lu1, Chunyan Huo1
1Department of Gastroenterology, The Affliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Scientific reports
|August 23, 2023
概括
非癌症死亡,包括心脏病和感染,在胆囊癌 (GBC) 患者中是显著的. 与普通人群相比,GBC幸存者面临的非癌症死亡风险更高,这影响了长期的健康管理.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在胆囊癌 (GBC) 患者中,癌症以外的死亡原因仍然不完全理解.
- 评估非癌症死亡风险对于全面的GBC患者护理至关重要.
研究的目的:
- 评估GBC患者非癌症死亡率的原因和危险因素.
- 为了将GBC患者的非癌症死亡率与普通人群进行比较.
主要方法:
- 从监测,流行病学和最终结果 (SEER) 数据库分析了2000-2017年间诊断的11,927名GBC患者.
- 计算非癌症原因的标准化死亡率 (SMRs).
- 多变量竞争性风险分析,以确定非癌症死亡的预测因素.
主要成果:
- 心血管疾病 (43.3%),其他原因 (34.4%) 和传染病 (8.6%) 是最常见的非癌症死亡原因.
- 与一般人群相比,GBC患者心脏病 (1.58),败血症 (3.21) 和糖尿病 (1.97) 的SMR较高.
- 大多数非癌症死亡 (39.4%) 发生在诊断后3年以上.
结论:
- 非癌症原因在GBC幸存者中占死亡率的很大一部分.
- 胆囊癌患者面临着因非癌症疾病死亡的风险较高.
- 这些发现强调了需要综合健康管理策略,以解决GBC幸存者的非癌症风险.
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