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代价 脊椎和横脊椎关节参与脊椎关节炎的代价
Emine Büşra Ata1, Gamze Durhan2, Emre Bilgin3
1Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.
International journal of rheumatic diseases
|August 24, 2023
概括
脊椎关节炎 (SpA) 患者表现出显著的 costovertebral 和 costotransverse 关节损伤,特别是在结性脊椎炎 (AS) 中,影响胸部扩张. 胸部CT扫描可以帮助早期检测康复.
科学领域:
- 类风湿病学 类风湿病学
- 放射学 放射学是一门学科.
- 整形外科 整形外科 整形外科
背景情况:
- 脊椎关节炎 (SpA) 经常影响轴和外周关节,包括 costovertebral (CV), costotransverse (CTr),硬骨关节 (SC) 和手腕关节 (MS).
- 临床评估这些特殊的联合参与SPA需要进一步调查.
研究的目的:
- 通过使用胸部计算机断层扫描 (CT) 来评估CV,CTr,SC和MS关节参与患者的患病率和严重程度.
- 为了比较不同的SpA亚型和类风湿性关节炎 (RA) 和非风湿性疾病对照的关节参与.
- 探索关节参与和临床参数 (如胸部膨胀) 之间的关系.
主要方法:
- 对281名SPA患者的胸部CT扫描进行了回顾性分析 (分为结性脊柱炎 (AS),非放射性轴性SPA和牛皮关节炎).
- 与30名RA患者和30名非风湿性对照人群进行比较.
- 放射性评估24 CV,20 CTr,2 SC和1 MS关节的患者,根据严重程度分级 (正常到严重).
主要成果:
- 在SpA疾病组之间观察到总CV和CTr联合得分的显著差异 (p < .001).
- 与女性AS患者相比,男性AS患者的CV和CTr关节参与得分较高.
- 在AS患者中,胸部扩张和心血管/心关节参与之间发现了强烈的负相关性 (r = -0.703和r = -0.763,分别;p < .01).
- 在CV/CTr关节评分和修改后的Stokes Ankylosing Spondylitis脊柱评分之间存在正相关性 (p < .05).
- 在MS和SC联合参与方面没有发现显著的关联.
结论:
- 脊椎关节和脊椎关节的干扰在结性脊髓炎中更严重,并对胸部扩张产生负面影响.
- 胸部CT成像,即使是出于其他原因进行的,也可用于检测SPA的早期关节变化.
- 使用现有的CT扫描可能有助于及时启动旨在保持胸部移动性的康复计划.
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