情境意识和主动参与预测了青少年和年轻成年人使用混合闭环的更高时间范围
Laurel H Messer1,2, Paul F Cook2, Stephen Voida3
1Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Pediatric diabetes
|August 24, 2023
概括
使用混合闭环系统 (HCL) 治疗1型糖尿病的青少年表明,了解葡萄糖水平和主动系统使用改善了血糖控制. 反应性参与和低估葡萄糖预测较低的时间在范围 (TIR).
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 生物医学工程 生物医学工程
背景情况:
- 患有1型糖尿病 (T1D) 的青少年和年轻人通常由于自我管理的挑战而表现出低于最佳的血糖控制 (高HbA1c).
- 混合式闭环系统 (HCL),如带有Control-IQ技术的t:slim X2,在这个人群中提供了改善葡萄糖管理的潜力.
- 了解用户参与和情境意识对于优化HCL治疗效果至关重要.
研究的目的:
- 在使用Control-IQ HCL系统时,评估青少年对血糖控制的情境意识.
- 评估系统参与行为与日常血糖控制 (Time in Range - TIR) 之间的关系.
- 用HCL技术确定影响青少年血糖结果的因素.
主要方法:
- 一项为期2周的前性研究,涉及使用Control-IQ系统的青少年 (15-25岁).
- 数据收集包括系统参与 (例如,螺栓,警报) 和自我报告的葡萄糖意识没有检查.
- 混合效应模型被用来将行为和意识与TIR相关联 (目标:70-180 mg/dL).
主要成果:
- 情境意识与自上次血糖检查以来的时间没有相关性.
- 较低的TIR与低估葡萄糖水平,增加CGM警报和更频繁的动相关.
- 较高的TIR与响应CGM警报和准确输入碳水化合物数据进行玻尿酸计算有关.
结论:
- 情境意识是TIR的独立预测因素,强调了它在青少年糖尿病自我管理中的重要性.
- 积极的HCL系统参与与更好的TIR相关,而反应性的参与与较差的结果有关.
- 未来的干预措施应侧重于提高用户的意识和自我管理技能,以获得有效的HCL治疗.
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