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油基和水基对比介质之间的生育结果比较在歇斯托索平摄影期间:一个元分析

Jun Chen¹, Shushu Liu¹, Jianguo Lu¹

¹Department of Medical Imaging, People's Hospital of Fengjie, Chongqing 404600, P.R. China.

Experimental and therapeutic medicine

|August 24, 2023

概括

油基对比介质显著改善生育结果,包括临床怀孕,正在进行的怀孕和活产率,与水基介质相比,油基对比介质在歇斯托索平摄影 (HSG) 期间显著改善生育结果. 这一元分析证实了以石油为基础的媒体.

科学领域:

生殖医学生殖医学
医疗成像医学成像

背景情况:

歇斯托索平摄影 (HSG) 通常使用水基或油基对比介质.
关于在HSG期间以油为基础的对比剂的潜在优异生育增强效果存在争论.
了解比较生育结果对于优化HSG程序至关重要.

研究的目的:

在HSG中进行一个元分析,比较基于油和基于水的对比介质之间的生育结果.
评估对比介质类型对临床怀孕,正在进行的怀孕和活产率的影响.

主要方法:

在多个数据库 (Web of Science,PubMed,EMBASE,Cochrane,CNKI,Wanfang,CSTJ) 进行系统的文献搜索,截至2022年11月10日.
包括11项研究,涉及2,462名患者 (以油为基础) 和2,830名患者 (以水为基础).
使用随机效应模型计算相对风险 (RR) 和95%置信区间 (CI) 的元分析;使用Egger和Begg的测试评估出版偏差.

主要成果:

基于油的对比剂显著增加了临床怀孕率 (RR:1.29,95% CI:1.07-1.54,P=0.006).
持续怀孕 (RR: 1.39,95% CI: 1.22-1.59,P<0.001) 和活产率 (RR: 1.41,95% CI: 1.07-1.87,P=0.016) 在以油为基础的介质中也显著上升.
在两种类型的对比介质之间,没有观察到两种类型的对比介质之间的流产或宫外妊娠率的显著差异.

结论:

与水基对比剂相比,油基对比剂在接受HSG的患者中显示出显著的提高生育效果.
这些发现支持使用以油为基础的对比媒介,以改善HSG后的生育结果.
油基介质与流产或子宫外妊娠等不良妊娠结果的风险增加无关.

关键词:

通过hysterosalpingography,可以检测出这些情况.不孕不育不孕不育不孕不育油性对比介质是以油为基础的对比介质.怀孕的结果.基于水的对比介质是基于水的对比介质.

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