我们如何治疗八十多岁的脑转移患者?
Carsten Nieder1,2, Nicolaus H Andratschke3, Anca L Grosu4
1Department of Oncology and Palliative Medicine, Nordland Hospital, Bodø, Norway.
Frontiers in oncology
|August 24, 2023
概括
脑转移的八代人通常可以耐受癌症治疗,但脆弱会影响资格. 多学科评估对于优化老年人群的护理和结果至关重要.
科学领域:
- 老年瘤学 老年瘤学
- 神经瘤学神经瘤学
- 癌症治疗方法 癌症治疗方法
背景情况:
- 患有癌症,特别是脑转移的八代人 (80岁以上) 是一个不断增长和脆弱的患者群体.
- 虚弱,并发症和癌症的传播显著影响老年人的治疗资格和治疗结果.
- 当前的预后得分可能不准确地反映了八十岁人口的结果.
研究的目的:
- 审查各种瘤治疗的耐受性和疗效,在生物学上更年轻的,独立的八岁老人脑转移.
- 为突出多学科评估对这一患者群体的重要性.
- 为了评估治疗结果和八十岁的预后得分的局限性.
主要方法:
- 对治疗实例的审查,包括手术,放射性手术,全身疗法,以及脑转移的八岁老人的最佳支持性护理.
- 讨论影响治疗决策和结果的因素,如年龄,脆弱性和性能状况.
- 对现有文献和预后得分的分析,考虑到回顾性研究中的选择偏差.
主要成果:
- 在生物学上更年轻,独立的八十岁老人通常能很好地忍受瘤治疗.
- 脆弱性显著限制了获得化疗和手术等治疗的资格.
- 放射性手术在回顾性分析中显示,与全脑放射治疗相比,放射性手术的生存率更令人鼓舞,尽管存在选择偏差.
结论:
- 多学科评估对于管理脑转移的八十岁人来说至关重要,考虑到他们独特的脆弱性.
- 治疗决策必须平衡瘤学目标与功能状态和潜在的毒性.
- 需要进一步的前性研究,专注于八十岁的患者,以改进治疗策略和改善生存结果.
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