在健康,多样化的产科医生群体中,基线旋转血小板造血计 (ROTEM) 值,以及由怀孕引起的并发病引起的参数变化
Antonio Gonzalez Fiol1, Jin Yoo2, David Yanez1
1Department of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USA.
概括
这项研究确定了美国各种产科医生群体的基线旋转血栓形成仪 (ROTEM) 值,发现黑人种族,肥胖和子宫前与高凝血概况有关,有助于产后出血管理.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 照顾点检测检测 照顾点检测
背景情况:
- 旋转性血小板造影仪 (ROTEM) 对于治疗产后出血至关重要.
- 美国不同产科人群的基线ROTEM值缺乏.
- 本研究通过建立基线ROTEM值来解决这一差距.
研究的目的:
- 在异质的美国产科医生群体中确定基线ROTEM值.
- 评估ROTEM参数与并发症,种族和社会经济因素之间的关联.
- 告知有效的产后出血管理策略.
主要方法:
- 对于患产后出血风险较高的妇女的ROTEM值的回顾性审查.
- 将其分为健康和并发症组,并根据特定的排除标准进行分类.
- 分析INTEM,EXTEM和FIBTEM参数,包括A10和A20值.
主要成果:
- 485名妇女符合入选标准;267名妇女被归类为健康.
- 母亲平均年龄:32.2岁,BMI:34公斤/米2,妊娠年龄:35.4周.
- 在黑人或肥胖个体中观察到的INTEM,EXTEM和FIBTEM A10的增加;在亚洲个体或患有HELLP综合征的人群中减少.
结论:
- 确定的基线ROTEM值与欧洲研究一致.
- 黑人种族,肥胖和妊娠前与高凝血概况有关.
- 研究结果支持使用ROTEM进行个性化产后出血管理.
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