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Updated: Jul 18, 2025

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恩根类型的二类药物通过调节SRC/PI3K/Akt路径来抑制非小细胞肺癌细胞

Xin-Ye Wang1, Yu-Jue Wang1, Zi-Lin Hou1

  • 1Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, Engineering Research Center of Natural Medicine Active Molecule Research & Development, Liaoning Province, Key Laboratory of Natural Bioactive Compounds Discovery & Modification, Shenyang, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.

Natural product research
|August 24, 2023
PubMed
概括

来自Euphorbia植物的 Ingenane 类型的二甲 (ITD) 对非小细胞肺癌 (NSCLC) 显示出有前途. 这些化合物,如13-oxyingenol-dodecanoate (13OD),通过向SRC/PI3K/Akt通路来抑制NSCLC的生长.

关键词:
13氧醇-多德酸是13氧醇-多德酸的一种.非小细胞肺癌是非小细胞肺癌.在SRC/PI3K/akt路径中.基类型的四角体.

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