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Updated: Jul 18, 2025

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
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调控性类风湿病因子对PD-1具有特异性,并使用PD-1途径控制CD4 T淋巴细胞

Tatyana Khramova1,2, Liubov Beduleva1,2, Alexandr Sidorov1,2

  • 1Laboratory of Molecular and Cell Immunology, Department of Immunology and Cell Biology, Udmurt State University, Izhevsk, Russian Federation.

Immunological investigations
|August 24, 2023
PubMed
概括

调控性类风湿因子 (regRF) 通过结合编程死亡-1 (PD-1) 来向激活的CD4+T细胞. 这种相互作用由regRF的共享帕拉托普介导,启动细胞死亡,从而降低自身免疫反应的调节.

关键词:
CD4 T 淋巴细胞 CD4 淋巴细胞在IgG Fc片段中.控制自身免疫性的控制.编程死亡-1-1 的程序.调节性类风湿病因子的调节性因素

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