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推进RNA3D结构预测:在CASP15中探索层次和混合方法

Jun Li1, Sicheng Zhang1, Shi-Jie Chen1

  • 1Department of Physics, Department of Biochemistry, and Institute for Data Science and Informatics, University of Missouri, Columbia, Missouri, USA.

Proteins
|August 24, 2023
PubMed
概括

本研究提出了RNA结构预测的混合方法,在2D中达到高精度,在3DRNA结构预测中达到中度精度. 该方法在CASP15竞赛中排名第二,证明了其可靠性.

关键词:
在CASP15中,CASP15是指CASP15.这就是IsRNARNA.预测RNA结构 预测RNA结构在此之前,RNJP RNAJP这就是Vfold2D-MC.在VfoldMCPXX中使用.粗粒模型的粗粒模型

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Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
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