2000年至2019年哥斯达黎加出生缺陷的基于人口的流行率和趋势
Adriana Benavides-Lara1, María de la Paz Barboza-Argüello1
1Costa Rican Birth Defects Register Center (CREC), Costa Rican Institute of Research and Education in Nutrition and Health (INCIENSA), Cartago, Costa Rica.
Birth defects research
|August 24, 2023
概括
哥斯达黎加的出生缺陷 (BD) 呈现上升趋势,从2000年至2019年每年增加3.7%. 这种增长与改善的监控系统有关,呼吸道,心脏和神经系统缺陷的显著增加.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生殖健康 生殖健康
背景情况:
- 出生缺陷是哥斯达黎加婴儿死亡的一个重要原因.
- 分析BD患病率和趋势对于公共卫生干预至关重要.
研究的目的:
- 分析哥斯达黎加2000年至2019年出生缺陷的流行率和趋势.
- 为了确定二十年期间BD趋势的重大变化.
主要方法:
- 来自哥斯达黎加出生缺陷登记册的BD数据的描述性分析.
- 加入点回归以识别趋势变化并计算年度百分比变化 (APC) 和平均年度百分比变化 (AAPC).
- 普森回归用于估计流行率,并比较分期 (2000-2009年与2010-2019年).
主要成果:
- 在2000年至2019年期间,BDs影响了2.3%的活产,其中73%是重大缺陷.
- 观察到BD的总体上升趋势显著 (AAPC +3.7%),在2005-2013年间显著增加 (APC +11.3%).
- 呼吸系统缺陷 (+11.7%),先天性心脏缺陷 (+9.5%) 和神经系统缺陷 (+8.5%) 的增长趋势最高.
结论:
- 在过去的20年里,出生缺陷在哥斯达黎加显示出明显的上升趋势.
- 改善国家BD监测系统可能有助于观察到报告病例的增加.
- 需要有针对性的公共卫生战略来应对日益增长的特定出生缺陷的患病率.
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