肺癌,结肠癌,乳腺癌和前列腺癌的诊断年龄:国际比较研究
Hana Zahed1, Xiaoshuang Feng1, Mahdi Sheikh1
1Genomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.
International journal of cancer
|August 24, 2023
概括
全球癌症诊断年龄差异很大. 在调整人口年龄后,肺癌,结肠癌,乳腺癌和前列腺癌等常见癌症的中位数诊断年龄在全球范围内有10年的差异,反映了风险因素和查.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 癌症研究 癌症研究
背景情况:
- 观察到癌症诊断时的平均年龄的国际变化.
- 人口年龄结构的差异可以影响诊断时的粗略平均年龄.
- 需要了解诊断时的真实年龄,独立于人口统计数据的变化.
研究的目的:
- 评估常见癌症诊断时平均年龄的国际变化.
- 为了调整人口年龄结构的差异,使用间接标准化.
- 探索潜在的驱动因素的年龄在诊断变化,如风险因素和查.
主要方法:
- 利用了五大洲癌症发病率 (CI5) 第十一卷数据库 (2008-2012).
- 包括来自65个国家的基于人口的登记册的癌症诊断.
- 计算了肺癌,结肠癌,乳腺癌和前列腺癌诊断时的粗略和间接标准化的中位数年龄.
主要成果:
- 标准化显示,平均年龄的变化高达10年,在低收入和中等收入国家 (LMICs) 经常增加,在高收入国家 (HICs) 减少.
- 诊断时的平均年龄在标准化后的范围是肺癌和结肠癌的12年,女性乳腺癌和前列腺癌的10年.
- 结肠癌在LMICs和HICs中被诊断为年轻的;前列腺癌在LMICs和HICs中被诊断为年长的. 在高吸烟率的国家,肺癌的诊断年龄较小. 在东亚,中东和非洲,女性乳腺癌诊断年轻.
结论:
- 在考虑到人口年龄结构后,癌症诊断时的平均年龄的国际差异仍然存在.
- 变化可能反映出人口层面的风险因素 (如吸烟) 和癌症控制措施 (如查) 的差异.
- 调查结果强调了根据人口和流行病学背景制定量身定制的癌症控制策略的必要性.
更多相关视频
07:47Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
Published on: September 15, 2023
1.5K
07:44Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
10.2K
相关概念视频
01:21Cancer Survival Analysis
383
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
383
02:20Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
01:25Statistical Methods for Analyzing Epidemiological Data
408
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
408
02:59Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K