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一项关于抗结核药物异化的非酶性降解的DFT研究

Wirachai Pornin1, Ratchanee Phatchana1, Titikan Somboon1

  • 1Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan, KhonKaen Campus, KhonKaen, 40000, Thailand.

Journal of molecular modeling
|August 24, 2023
PubMed
概括

异化 (INH) 的降解是结核病治疗稳定性的关键因素,主要通过分体化,然后通过水解发生. 了解这些非酶反应对于开发改进的药物配方和应用至关重要.

关键词:
生物降解 生物降解在 DFT 方面,它是最重要的.降解降解是一种降解.水解是指水解过程中的水解.在INH中,我们可以伊索尼亚齐德的使用方法作为一个核爱者.制药用共晶体的使用情况这就是为什么TBTBTBTB塔图默斯 (Tautomers) 是一个字符串.结核病是一种疾病.

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