在三个纵向研究中,儿童和青少年时期的精神病症状轨迹:用混合模型进行综合数据分析
Rashelle J Musci1, Joseph M Kush2, Katherine E Masyn3
1Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Room 331, Baltimore, MD, 21205, USA. rmusci1@jhu.edu.
概括
类似精神病的经历 (PLEs) 在儿童时期很常见,并且与以后的心理健康问题有关. 这项研究确定了三个儿童PLE轨迹:持久,改善和没有,使用综合数据分析.
科学领域:
- 儿童和青少年精神病学 儿童和青少年精神病学
- 发展心理学 发展心理学
- 心理健康研究 心理健康研究
背景情况:
- 类似精神病的经历 (PLEs) 在童年时代很普遍,是不良心理健康结果的重要风险因素.
- PLEs与各种心理健康诊断有关,使他们成为早期干预的潜在目标.
- 关于非临床儿童群体PLE轨迹的纵向数据有限.
研究的目的:
- 探索整个童年精神病类经历 (PLEs) 的纵向轨迹.
- 通过协调来自多个基于学校的随机对照试验的数据来识别PLE中的异质性.
- 应用综合数据分析 (IDA) 和增长混合模型来理解PLEs的发展模式.
主要方法:
- 从三个基于学校的随机对照试验与纵向随访的统一数据.
- 采用增长混合模型的综合数据分析 (IDA).
- 识别了潜伏轨迹类,代表了随着时间的推移不同的PLE模式.
主要成果:
- 确定了三种不同的轨迹类别:持续的PLEs,改善的PLEs和没有PLEs.
- 与没有PLE的儿童相比,改善PLE类的儿童更有可能是男性,并表现出更高的基线侵略性和破坏性行为.
- 在多项研究中证明了使用IDA用于纵向混合物建模的可行性和复杂性.
结论:
- 童年精神病类经历表现出多样化的纵向轨迹,具有明显的持久性和改善模式.
- 了解这些轨迹,特别是改善群体的特征,可以为有针对性的预防干预提供信息.
- 这项研究突出了将多样化的数据集用于复杂的纵向分析的方法论进步和挑战.
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