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免疫检查点抑制剂用于儿童皮格B类晚期肝细胞癌:系统性审查和元分析

Enrui Xie1, Yee Hui Yeo2, Bernhard Scheiner3,4

  • 1Department of Infectious Diseases, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

JAMA oncology
|August 24, 2023
PubMed
概括

免疫检查点抑制剂 (ICI) 在患有Child-Pugh B肝功能的晚期肝细胞癌 (HCC) 患者中显示出相似的安全性,但反应率和生存率较低. 对这一群体需要进行进一步的研究.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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