儿童白风的全球临床流行病学模式:系统性审查和元分析
Saeedeh Farajzadeh1, Maryam Khalili2, Majid Mirmohammadkhani3
1Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
BMJ paediatrics open
|August 24, 2023
概括
这项研究显示,儿童白风在女性中更常见,主要是非细分型,其中,焦点和面型最为普遍. 模式在全球范围内有所不同,这凸显了对儿科白风的进一步研究的需要.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 与成人发病病例相比,儿童白风具有不同的特征.
- 关于儿科白风的临床流行病学模式的系统审查有限.
- 这项研究解决了对儿童白风特征进行全面审查的需要.
研究的目的:
- 系统地审查和分析儿科人口中白风的临床流行病学模式.
- 整合现有关于儿童白风的流行率,类型和相关因素的数据.
- 提供关于儿科白风呈现的全球变异性的见解.
主要方法:
- 在2022年6月使用MeSH术语在PubMed,Scopus和Web of Science进行了全面的文献搜索.
- 符合条件的研究通过严格的三步过程进行了选择.
- 从涉及4365名儿童的17项研究中提取的临床流行病学数据,使用STATA的元分析进行了分析.
主要成果:
- 该元分析包括4365名受试者,女性占56.8% (女性与男性的比例为1.3:1).
- 非细分性白风是最常见的 (总比为4.6:1),其中包括型 (42.49%),焦点型 (27.21%) 和面型 (17.8%).
- 在16.88%的患者中报告了阳性家族史,因地区而异,并观察到Koebner现象 (25.47%) 和白血病 (18.52%).
结论:
- 儿童白风在女性中患病率更高,主要是非细分型.
- 观察到的最常见的亚型是粗,焦点和面白风.
- 儿童白风的临床流行病学模式存在显著的地理差异.
关键词:
流行病学流行病学相关概念视频
Changes in Skin Color: Clinical Perspectives
2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Prevalence and Incidence
627
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
627
Skin Diseases and Disorders
3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Pigmentation
2.5K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.5K
Bias in Epidemiological Studies
352
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
352


