流行病学研究中心的测量不变度,在六个不同的干预试验中和跨越六个不同的干预试验中的抑郁度
Irina Bergenfeld1, Nadine J Kaslow2, Kathryn M Yount1
1Department of Global Health, Rollins School of Public Health, Emory University.
Psychological assessment
|August 24, 2023
概括
流行病学研究中心Scale-Depression (CES-D) 在试验中显示了测量不变性,但不是在不同的人口中. 删除积极影响项可以提高其对抑郁症查的交叉研究有效性.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 跨文化心理学 跨文化心理学
- 临床试验方法论 临床试验方法论
背景情况:
- 抑郁症是一个重要的全球健康问题,文化差异使症状测量变得复杂.
- 流行病学研究中心Scale-Depression (CES-D) 被广泛使用,但其因子结构和跨不同人群和干预措施的不变性需要进一步调查.
- 准确测量抑郁症状对于临床试验和全球健康研究至关重要.
研究的目的:
- 分析低收入和中等收入国家中CES-D的因数结构和测量不变性.
- 在临床试验中,评估CES-D在治疗/对照组和随时间变异的不变性.
- 检查交叉研究的不变性,并确定可能导致抑郁症测量不变性的项目.
主要方法:
- 来自低收入和中等收入国家的六项临床试验的二次分析.
- 探索性和确认性因素分析以确定CES-D的因素结构.
- 多组确认分析以评估研究内部和跨研究的测量不变性.
主要成果:
- 一个单维的CES-D模型,不包括积极影响项目,在试验中证明了随时间的推移和跨治疗臂的不变性.
- 然而,该尺度在不同试验中表现出显著的不变性,表明文化或人口特异性差异.
- 与积极影响相关的特定项目被确定为这种交叉研究非不变性的潜在驱动因素.
结论:
- 在排除积极影响项时,CES-D似乎是特定试验背景下抑郁症状的有效衡量标准.
- 使用CES-D在不同人群中解释元分析或多站点研究的发现时,建议谨慎.
- 需要进一步的研究来完善抑郁症测量工具的跨文化和全球应用.
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