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Updated: Jul 18, 2025

Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells
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Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells

Published on: September 9, 2021

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人类血栓蛋白受体构造的调节将JAK2 V617F驱动的激活与细胞因子诱导的刺激脱离

Nicolas Papadopoulos1,2,3, Ajda Pristavec1, Audrey Nédélec1,2,3

  • 1de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.

Blood
|August 24, 2023
PubMed
概括

向血栓形成素受体 (TpoR) 提供了针对骨髓增殖性瘤 (MPNs) 的新策略. 研究人员确定了特定的TpoR构造,可以选择性抑制MPN中JAK2 V617F驱动的激活.

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