在像塞拉利昂这样的低收入,高负担环境中,对孕产妇肺炎球菌疫苗的成本效益分析
Gizem M Bilgin1, Syarifah Liza Munira1, Kamalini Lokuge1
1National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
PLOS global public health
|August 24, 2023
概括
孕产妇肺炎球菌疫苗在低收入国家提供了具有成本效益的婴儿保护,特别是从社会角度来看. 疫苗定价对于这些国家的广泛采用和自我融资至关重要.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 卫生经济学 卫生经济学
背景情况:
- 母婴肺炎球菌疫苗接种是一种保护婴儿免受严重肺炎球菌疾病的策略.
- 评估成本效益对于在低收入环境中实施新的公共卫生干预措施至关重要.
研究的目的:
- 评估母性肺炎球菌多糖体疫苗 (PPV) 计划的成本效益.
- 从塞拉利昂的医疗保健和社会角度分析成本.
主要方法:
- 使用动态传输模型来估计成本和健康结果.
- 计算包括直接的医疗保健成本,避免的成本和避免的生产力损失.
- 成本效益被衡量为每隔的残疾调整寿命年 (DALY).
主要成果:
- 从医疗保健的角度来看,母亲的PPV计划每天花费606美元,从社会角度来看,花费132美元.
- 从社会角度来看,干预是具有成本效益的,但从塞拉利昂人均GDP (527美元) 的角度来看,从医疗保健角度来看是没有成本效益的.
- 敏感性分析表明,从医疗保健的角度来看,成本效益是可以实现的,而无需折扣健康益处或降低疫苗采购成本.
结论:
- 孕产妇肺炎球菌疫苗在低收入国家具有成本效益的潜力.
- 与供应商谈判疫苗价格对于低收入国家来说是必不可少的,以自我资助这种干预.
- 疫苗价格是孕产妇肺炎球菌疫苗接种计划成本效益的主要驱动因素.
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