哈特 (Catha edulis) 的第二次任务特异性口腔 dystonia - 一系列35个病例
Pettarusp Murzban Wadia1, Vaibhav Mathur1, Prashanth Lingappa Kukkle2
1Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India.
Parkinsonism & related disorders
|August 24, 2023
概括
哈特是一种精神刺激的灌木,可能会在也门男性中引起特定任务的Oro-mandibular dystonia (OMD). 早期识别这种情况对于预防残疾至关重要.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 遗传学 是一个遗传学.
背景情况:
- 卡特 (Catha edulis) 叶子在也门和阿拉伯半岛被以获得精神刺激作用.
- 耳双 dystonia (OMD) 是一种影响下肌肉的运动障碍.
研究的目的:
- 描述也门男性与口有关的一种独特的特定任务的OMD.
- 评估这些患者对Onabotulinum毒素A的临床特征和治疗反应.
主要方法:
- 在2009年至2020年期间,对OMD患者进行了多中心的回顾性分析,这些患者与卡特有关.
- 评估临床表现和对Onabotulinum毒素A治疗的反应.
主要成果:
- 35名也门男性平均年龄为44.31岁,有长时间的卡特史 (20.31年,每天5.16小时),出现了OMD.
- 大多数病例涉及下巴打开 (n=20),一些下巴关闭 (n=13) 或混合类型 (n=2).
- 在5名患者中观察到额外的语言性 dystonia.
结论:
- 由于哈特而导致的重复性下肌肉活动可能是特定任务OMD的致病因素.
- 承认这种关联对于预防受影响地区的残疾至关重要.
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