认知障碍和焦虑在接受移植的接受者中很普遍
Aleksandra Golenia1, Piotr Olejnik2, Norbert Żołek3
1Department of Neurology, Medical University of Warsaw, Warsaw, Poland.
Kidney & blood pressure research
|August 24, 2023
概括
认知障碍影响30%的脏移植接受者,影响他们的康复和预后. 需要进一步的研究来理解和解决移植后的认知衰退.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经心理学 神经心理学
- 移植医学 移植医学
背景情况:
- 认知障碍 (CI) 在末期病 (ESKD) 和移植 (KT) 接受者中很普遍.
- CI可以阻碍移植后的坚持,导致并发症和较差的结果.
- 抑郁和焦虑是ESKD患者常见的并发症.
研究的目的:
- 评估移植接受者认知障碍的发生率.
- 评估人口,临床和与治疗相关的变量对后KT认知功能的影响.
- 在这个患者群体中选抑郁和焦虑.
主要方法:
- 一个单一的中心,对56名成年KT接受者的横截面研究.
- 使用阿登布鲁克认知测试III (ACE-III) 评估认知功能.
- 使用医院焦虑和抑郁量表 (HADS) 选抑郁和焦虑.
主要成果:
- 30%的KT接受者表现出认知障碍.
- 患有CI的患者在所有认知领域的得分明显较低.
- 高等教育水平与更好的认知功能相关;没有发现与年龄,透析持续时间或免疫抑制剂有重大关联.
- 抑郁症和焦虑症的患病率分别为12.5%和27%.
结论:
- 认知障碍对接受移植的人来说是一个重大挑战.
- 多种移植前和移植后的因素可能会对认知功能产生负面影响.
- 进一步的研究对于阐明KT后认知功能的轨迹和特征至关重要.
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