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Updated: Jul 18, 2025

Fluorescence Anisotropy as a Tool to Study Protein-protein Interactions
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SASH1:一个新的Eph受体合作伙伴以及对SAM-SAM相互作用的洞察

Yuzhen Ding1, Qiangou Chen2, Hui Shan3

  • 1Shenzhen Key Laboratory for Neuronal Structural Biology, Biomedical Research Institute, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, China. Electronic address: https://twitter.com/dingyuzhen8.

Journal of molecular biology
|August 24, 2023
PubMed
概括

研究人员发现,SASH1 (含有1的SAM和SH3域) 通过其无菌阿尔法基因 (SAM) 域与Eph受体,特别是EphA8结合. 这种相互作用对调节EphA8激酶活性至关重要,对癌症有影响.

关键词:
"以弗所"的信号表示这就是SAM-SAM的相互作用.这就是SASH1的意义.癌症突变 癌症突变激酶活动激酶活性.

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