PTEN以DNA甲基化依赖的方式调节其伪基因在质母细胞中的表达

Tatyana F Kovalenko1, Bhupender Yadav2, Ksenia S Anufrieva3

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.

Biochimie
|August 24, 2023
PubMed
概括

在质母细胞瘤中,PTEN蛋白通过DNA甲基化调节IncPTENP1-S的表达. 这种长长的非编码RNA通过增加干细胞标记物和减少细胞粘附来促进癌症.

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