儿童和成年人的横侧髓炎
Eleonora Agata Grasso1, Valeria Pozzilli1, Valentina Tomassini1
1Department of Neurosciences, Imaging and Clinical Sciences, Institute of Advanced Biomedical Technologies (ITAB), University G. d'Annunzio of Chieti-Pescara, Chieti, Italy.
Handbook of clinical neurology
|August 24, 2023
概括
横脊髓炎是一种具有多种原因的炎症性脊髓疾病. 诊断包括MRI和CSF分析,年龄影响症状和治疗策略,以获得更好的结果.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 神经炎症是一种神经炎症.
背景情况:
- 横侧髓炎是一种非压缩性炎症性骨髓病,具有多种病因,包括感染,毒素和免疫媒介过程.
- 它可以表现为系统性疾病的一部分,如狼或作为一种主要的神经炎症状况,有时有未知的原因 (非发病性).
研究的目的:
- 总结横侧髓炎的原因,临床表现,诊断方法和管理策略.
- 突出年龄对症状,预后和治疗决策的影响.
- 用特定的抗体标记物来区分免疫介导的表型.
主要方法:
- 基于脊髓损伤水平的临床表现的审查.
- 使用脊髓磁共振成像 (MRI) 和脑脊液 (CSF) 检查进行诊断.
- 采用抗体检测 (抗水素4,抗髓-基细胞) 来识别免疫介导的表型.
主要成果:
- 临床表现因脊髓损伤水平而异,可能导致感觉运动缺陷和自主功能障碍.
- 发病时的年龄显著影响儿科和成人患者之间的症状,预后和治疗选择.
- 像MRI和CSF分析这样的诊断工具,以及特定抗体测试,有助于分类横向髓炎的亚型.
结论:
- 有效的管理和结果取决于识别横侧髓炎的潜在原因.
- 免疫抑制常用于免疫媒介形式,因为复发的风险更高.
- 考虑到发病时的年龄的个性化治疗方法对于优化患者护理和预后至关重要.
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